We are interested in how developing
cells make decisions about their differentiation
fate. Studies are conducted at a variety
of levels, from molecular biological
events controlling cell replication
and differentiation, through the determination
of cell fate, and where the nervous
system is concerned, synapse formation
and physiological function. Ongoing
projects for trainees comprise three
areas: (1) the role of endocrine and
neurotrophic factors in gene expression
by developing neurons; (2) effects
of drugs of abuse (especially nicotine),
environmental contaminants (especially
pesticides) and hormonal imbalances
on brain cell development; (3) pharmacotherapies
of preterm labor and their effects
on brain development.
